- Product Details
Keywords
- Bupivacaine Hydrochloride
- 14252-80-3
- C18H28N2O.ClH
Quick Details
- ProName: Bupivacaine Hydrochloride
- CasNo: 14252-80-3
- Molecular Formula: C18H28N2O.ClH
- Appearance: white solid
- Application: Anesthetic(local)
- DeliveryTime: within 3-7 day
- PackAge: As required
- Port: shanghai or other
- ProductionCapacity: 5 Metric Ton/Month
- Purity: 99%
- Storage: keep in dry and cool condition
- Transportation: by sea or by air
- LimitNum: 1 Kilogram
Superiority
Changzhou Xuanming Chemical Co., Ltd. is dedicated to the technology development, manufacturing, import and export chemicals, which are specialized in pharmaceutical intermediates, pesticide intermediate, industry of fine chemicals and custom synthesis. Now, we enjoy good reputation among customers and take favorable market share in domestic and at abroad.
Changzhou Xuanming Chemical CO., LTD is located in Northern Jiangshu Industry Park, we have modern manufacture bases and some laboratories, which can supply the key intermediate for your projects, and short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard. We have been abided by “treat technology as first, quality as basis, customers as God, and be honest and sincere”. It is our final aim to provide environmental and high technological products and meet customers’ requirements according to keep effors on developing new chemical fields.
Changzhou Xuanming Chemical CO., LTD promises to help you with heart and soul.
Details
Bupivacaine hydrochloride Basic information |
Product Name: | Bupivacaine hydrochloride |
Synonyms: | BUPIVACAINE HYDROCHLORIDE;(+,-)-1-butyl-2’,6’-pipecoloxylididemonohydrochloride,monohydrate;Bupivacaine Hydrochloride, USP;Bupivacaine hydrochloride 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride;Local Anesthetic Pharmaceutical Raw Material Bupivacaine HCl CAS 14252-80-3;1-butyl-2’,6’-pipecoloxylididehydrochloride(+-);2-piperidinecarboxamide,1-butyl-n-(2,6-dimethylphenyl)-monohydrochloride,m;ah-2250 |
CAS: | 14252-80-3 |
MF: | C18H28N2O.ClH |
MW: | 324.89 |
EINECS: | 627-065-3 |
Product Categories: | -;TAXOL;API-;Intermediates & Fine Chemicals;Pharmaceuticals;Sodium channel;Amines;Aromatics;Heterocycles |
Mol File: | 14252-80-3.mol |
Bupivacaine hydrochloride Chemical Properties |
Melting point | 249-2510C |
storage temp. | Refrigerator |
solubility | Soluble in water, freely soluble in alcohol. |
CAS DataBase Reference | 14252-80-3(CAS DataBase Reference) |
Safety Information |
Hazard Codes | T+ |
Risk Statements | 26/27/28 |
Safety Statements | 22-36/37/39-45 |
RIDADR | UN 2811 6.1/PG 2 |
WGK Germany | 3 |
RTECS | TK6125000 |
HazardClass | 6.1(b) |
PackingGroup | III |
HS Code | 2933399090 |
Toxicity | LD50 in mice (mg/kg): 7.8 i.v., 82 s.c. (Henn, Brattsand) |
Bupivacaine hydrochloride Usage And Synthesis |
Chemical Properties | White Solid |
Uses | antineoplastic |
Uses | Sodium channel blocker, local anesthetic |
Brand name | Marcaine (Hospira); Sensorcaine (AstraZeneca). |
Biological Functions | Bupivacaine hydrochloride (Marcaine, Sensorcaine) has particularly long action, and some nerve blocks last more than 24 hours; this is often an advantage for postoperative analgesia. Its use for epidural anesthesia in obstetrics has attracted interest because it can relieve the pain of labor at concentrations as low as 0.125% while permitting some motor activity of abdominal muscles to aid in expelling the fetus. The lower concentration minimizes the possibility of cardiac toxicity. Fetal drug concentrations remain low, and drug-induced neurobehavioral changes are not observed in the newborn. Bupivacaine also is approved for spinal anesthesia and is approximately four times more potent and more toxic than mepivacaine and lidocaine. It can be used with or without epinephrine. |