China (Mainland)
- Product Details
Keywords
- BleoMycin sulfate
- 9041-93-4
- C110H168N34O46S7
Quick Details
- ProName: BleoMycin sulfate
- CasNo: 9041-93-4
- Molecular Formula: C110H168N34O46S7
- Appearance: powder
- Application: For pharmaceutical
- DeliveryTime: 2-3day
- PackAge: 25KG/Cardboard bucket or as required
- Port: shanghai or other
- ProductionCapacity: 5 Metric Ton/Month
- Purity: 99（%）
- Storage: Store in dry, dark and ventilated plac...
- Transportation: by air or by sea
- LimitNum: 1 Kilogram
Superiority
| Bleomycin sulfate Basic information |
| Product Name: | Bleomycin sulfate |
| Synonyms: | BLEOMYCIN SULFATE CELL CULTURE TESTED;BLEOMYCIN SULFATE, BPC;BLEOMYCIN SULFATE FROM STREPTOMYCES VERT ICILLUS, LYOPH.;BLEOMYCIN SULFATE FROM STREPTOMYCES VERTICILLUS 0 TO 5 °C;Blocamicina;BLEMOYCIN SULFATE;3-[[2-[2-[2-[2-[4-[2-[6-Amino-2-[1-(2-amino-2-carbamoyl-ethyl)amino-2-carbamoyl-ethyl]-5-methyl-pyrimidin-4-yl]carbonylamino-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(3H-imidazol-4-yl)propanoyl]amino-3-hydroxy-2-methyl-pentanoyl]amino-3-hydroxy-butanoyl]aminoethyl]-1,3-thiazol-4-yl]-1,3-thiazol-4-yl]carbonylamino]propyl-dimethyl-sulfonium hydrogen sulfate;Bleomycin Sulfate, Blenoxane |
| CAS: | 9041-93-4 |
| MF: | C110H168N34O46S7 |
| MW: | 2927.17 |
| EINECS: | 232-925-2 |
| Product Categories: | Active Pharmaceutical Ingredients;UVCBs-biological;Intermediates & Fine Chemicals;Pharmaceuticals;Carbohydrates & Derivatives;Sulfur & Selenium Compounds;API;Inhibitors;-;BLENOXANE;antibiotic |
| Mol File: | 9041-93-4.mol |
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| Bleomycin sulfate Chemical Properties |
| Melting point | 200-204°C (dec.) |
| storage temp. | 2-8°C |
| solubility | H2O: 20 mg/mL |
| form | powder |
| color | white |
| Water Solubility | Soluble in water or DMSO |
| Merck | 14,1318 |
| CAS DataBase Reference | 9041-93-4(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | T,Xi |
| Risk Statements | 46-40-36/37/38-63 |
| Safety Statements | 53-36/37-45-36-26 |
| WGK Germany | 3 |
| RTECS | EC5991990 |
| F | 10 |
| Bleomycin sulfate Usage And Synthesis |
| Chemical Properties | White Powder |
| Uses | A group of related glycopeptide antibiotics. Bleomycin A2 is the main component of the bleomycin employed clinically. Antineoplastic |
| Uses | Bleomycin is a complex of 11 glycopeptide antitumour antibiotics originally isolated from Streptomyces verticillus in 1972. The dominant components of the complex are bleomycin A2 and B2, which typically represent >90% of the total weight . Bleomycins have found clinical application in the treatment of a range of tumours. Bleomycins act by intercalation of DNA and RNA. In the presence of oxygen and metal ions, notably copper and iron, bleomycins form a pseudo-enzyme that induces DNA cleavage. |
| Uses | Bleomycin is a complex of 11 glycopeptide antitumor antibiotics originally isolated from Streptomyces verticillus in 1972. The dominant components of the complex are bleomycin A2 and B2, which typically represent >90% of the total weight. Bleomycins have found clinical application in the treatment of a range of tumors. Bleomycins act by intercalation of DNA and RNA. In the presence of oxygen and metal ions, notably copper and iron, bleomycins form a pseudo-enzyme that induces DNA cleavage. |
| Brand name | Blenoxane (Bristol-Myers Squibb). |
| General Description | Bleomycin occurs as a white powder and is available in 15-and 30-U vials for reconstitution in water. It may be givenintravenously, intramuscularly, or subcutaneously. It is used in the treatment of squamous cell carcinoma of the headneck, cervix, penis, and vulva. It is also used in Hodgkin’sand non-Hodgkin’s lymphoma as well as testicular carcinoma.Unlabeled uses include the treatment of mycosis fungoides,osteosarcoma, and AIDS-related Kaposi sarcoma. |
| Veterinary Drugs and Treatments | Bleomycin has occasionally been used as adjunctive treatment of lymphomas, squamous cell carcinomas, teratomas, and nonfunctional thyroid tumors in both dogs and cats. Recent work has demonstrated that bleomycin may be promising for intralesional treatment for a variety of localized tumors with or without concomitant electropermeabilization. |
| Bleomycin sulfate Preparation Products And Raw materials |
| Preparation Products | PEPLOMYCIN |
| Raw materials | Potassium dihydrogen phosphate-->Zinc sulphate-->Disodium edetate dihydrate-->streptomyces avermifilis-->Dithizone-->Cation exchange resin,weak acidic acrylic acid |
Details
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